O11 Outcome measures in idiopathic inflammatory myositis

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Clinical Usefulness of Autoantibodies in Idiopathic Inflammatory Myositis

One of the most important characteristics of systemic autoimmune diseases, including idiopathic inflammatory myopathies (IIM), is the immune response to self-antigens manifested by the production of autoantibodies that recognize a variety of cytoplasmic and nuclear antigens. In the last 40 years, autoantibodies of patients with IIM have been investigated; however, some of the fundamental questi...

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[Myositis specific and myositis associated autoantibodies in idiopathic inflammatory myopathies: a serologic study of 46 patients].

OBJECTIVE To characterize serum autoantibody profiles of patients with idiopathic inflammatory myopathies (IIM) by searching for myositis-specific (MSA) and myositis-associated (MAA) antibodies with sensitive and specific laboratory tests. METHODS We tested the sera from 46 Caucasian patients diagnosed as affected with IIM at the Division of Rheumatology of Padova University (21 polimyositis,...

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Clinical outcome measures in juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA), as a chronic condition, is associated with significant disease- and treatment-related morbidity, thus impacting children's quality of life. In order to optimize JIA management, the paediatric rheumatologist has begun to regularly use measurements of disease activity developed, validated and endorsed by international paediatric rheumatology professional socie...

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The Myositis Autoantibody Phenotypes of the Juvenile Idiopathic Inflammatory Myopathies

The juvenile idiopathic inflammatory myopathies (JIIM) are systemic autoimmune diseases characterized by skeletal muscle weakness, characteristic rashes, and other systemic features. In follow-up to our study defining the major clinical subgroup phenotypes of JIIM, we compared demographics, clinical features, laboratory measures, and outcomes among myositis-specific autoantibody (MSA) subgroups...

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Monozygotic twins with distinct forms of idiopathic inflammatory myositis.

HTLV-I carrier showed a relatively small size of ectopic GC whose CXCL13 expression pattern was similar. However, interestingly, the MNCs of HAM–pSS patients demonstrated no expression of CXCL13. In contrast to CXCL13, CXCL12 was commonly expressed on ductal epithelial cells of all the pSS patients irrespective of anti-HTLV-I antibody. In a normal subject, no expression of CXCL13 was observed w...

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ژورنال

عنوان ژورنال: Indian Journal of Rheumatology

سال: 2011

ISSN: 0973-3698

DOI: 10.1016/s0973-3698(11)60100-3